Merel Kindt and her team demonstrated that fear memory can be deleted in humans (Kindt et al. 2009). This was achieved by the oral administration of β-adrenergic receptor antagonist propranolol before the reactivation of memory. They propose that their strategy of disrupting the (re-) stabilization of a memory after retrieval (reconsolidation) could pave the way […]
Posts Tagged ‘Memory’
Reading the mind’s eye: Online detection of visuo-spatial working memory and visual imagery in the inferior temporal lobe
Posted on behalf of Jaime Martinez: The authors of the present work studied the extent to which visual brain regions participate in non-sensory cognitive processes of visual representation. To this end, they evaluated the role of ventral visual pathway areas in visual imagery and working memory by analyzing intracerebral EEG recordings from the left inferior […]
Identification of a genetic cluster influencing memory performance and hippocampal activity in humans
In this study the authors investigated molecular pathways associated with memory formation. They used the behavioral genetics approach to identify genetic variations related to memory performance. An additional fMRI-study was conducted to validate their genetic findings as well as to capture brain activity related to the genotype. Out of 336 healthy subjects that underwent an […]
Protein degradation and fear memory
Recently it has been shown that hippocampal protein degradation via the ubiquitin proteasome system (UPS) is a prerequisite for reconsolidation of associative fear memory. Nevertheless the results for the role of hippocampal UPS mediated protein degradation in the consolidation of memory remain contradictory. Now Jarome et al. present data, suggesting that consolidation of fear memory […]
Die