NeuroJC

Neuro* Journal Club at the Free University Berlin

Stimulus onset quenches neural variability: a widespread cortical phenomenon

This article focuses on one of the basic properties of the cortical network that is widely considered as noise and mostly averaged out during the experimentation. The neural response is incompletely characterized without focusing on the ongoing activity that apparently gives rise to variable responses to the same stimulus situation. The across-trial membrane potential (Vm) variability and firing rate variability are quantified before and after the onset of the stimulus. Their findings suggest the variability observed is reduced after the stimulus and onset of stimulus improves the stability of the cortical network.

Reference:
Churchland MM, Yu BM, Cunningham JP, Sugrue LP, Cohen MR, Corrado GS, Newsome WT, Clark AM, Hosseini P, Scott BB, Bradley DC, Smith MA, Kohn A, Movshon JA, Armstrong KM, Moore T, Chang SW, Snyder LH, Lisberger SG, Priebe NJ, Finn IM, Ferster D, Ryu SI, Santhanam G, Sahani M, & Shenoy KV (2010). Stimulus onset quenches neural variability: a widespread cortical phenomenon. Nature neuroscience, 13 (3), 369-78 PMID: 20173745

Der Beitrag wurde am Sunday, den 3. June 2012 um 23:17 Uhr von Sathishk veröffentlicht und wurde unter General abgelegt. Sie können die Kommentare zu diesem Eintrag durch den RSS 2.0 Feed verfolgen. Sie können einen Kommentar schreiben, oder einen Trackback auf Ihrer Seite einrichten.

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