Merel Kindt and her team demonstrated that fear memory can be deleted in humans (Kindt et al. 2009). This was achieved by the oral administration of β-adrenergic receptor antagonist propranolol before the reactivation of memory. They propose that their strategy of disrupting the (re-) stabilization of a memory after retrieval (reconsolidation) could pave the way […]
Posts Tagged ‘Fear’
Protein degradation and fear memory
Recently it has been shown that hippocampal protein degradation via the ubiquitin proteasome system (UPS) is a prerequisite for reconsolidation of associative fear memory. Nevertheless the results for the role of hippocampal UPS mediated protein degradation in the consolidation of memory remain contradictory. Now Jarome et al. present data, suggesting that consolidation of fear memory […]
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